Fungi antioxidant pharmacological effect is related to the amount of phenolic compounds that the mushroom contains, just as it has been seen in grapes and wine.
Just like in the plant kingdom, more and more metabolites with antioxidant capacity are found in the fungi kingdom every year. Thus, antioxidants have been detected in common mushrooms sold in supermarkets such as: oyster mushroom (Pleurotus ostreatus), common mushroom (Agaricus bisporus) or shiitake (Lentinus edodes).
There are also mushrooms that are a natural source of powerful antioxidants. Thus the King Trumpet Mushroom itself (Pleurotus eryngii), consumed in many regions, has 40 times more antioxidant power than wheat germ, virtue also present in reishi (Ganoderma lucidum) since both fungi contain high quantities of "ergotioneina", one of the active molecules with the greatest antioxidant power known on the planet.
Pure reishi mushroom powder (Ganoderma lucidum) ready to be added to breakfast. Photo courtesy of MundoReishi.
Regarding the different antioxidant molecules of fungi, various operating mechanisms have been put forward:
Direct effects: due to reductive fungal metabolites.
Indirect effects: due to fungal substances that activate the body's antioxidant defense system: superoxide dismutase, glutathione peroxidase, catalase...